I haven't played the game yet, but I feel like I'd probably go with the neutral path. Not killing enemies and killing every single one seems like it'd be pretty difficult, but something I'd maybe be interested in in subsequent playthroughs. For my first one I'd definitely go with neutral though.
I'm not too sure which path I'll take. I figure it out once I get started on playing it. I want to take the pacifist route, but my mind may change before I start playing the game.